Hepatoprotective activity of Mitragyna speciosa Korth. on liver damage
NOPR - NISCAIR Online Periodicals Repository
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Title |
Hepatoprotective activity of Mitragyna speciosa Korth. on liver damage
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Creator |
Panjaitan, R G P
Mery, M W |
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Subject |
Kratom leaves
Liver histopathological Serum enzymes Tuak |
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Description |
133-139
This study aims to evaluate the protection and restoration capacity of kratom leaves extracts on liver damage caused by tuak. Group A consist of 12 mice and divided into A1 administered 0.5 mL/20 g body weight aquadest, A2 administered kratom leaves ethanol extract at dose 0.29 mg/20 g body weight and A3 administered silymarin at dose 0.70 mg/20 g body weight on days 1 to 7, then continued given tuak at dose 0.26 mL/20 g body weight on days 8 to 14. Group B consist of 12 mice and divided into B1, B2, and B3, on days 1 to 7 they were administered tuak at dose 0.26 mL/20 g body weight then continued with aquadest at dose 0.5 mL/20 g body weight (B1), kratom leaves ethanol extract at dose 0.29 mg/20 g body weight (B2), and silymarin at dose 0.70 mg/20 g body weight on days 8 to 14 (B3). The average levels of ALT enzyme in the treatment groups respectively showed 29.13±0.40 U/L (A1); 25.25±0.69 U/L (A2); 20.51±1.00 U/L (A3) and 31.20±0.47 U/L (B1); 26.95±0.62 U/L (B2); 23.31±0.89 (B3) (p |
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Date |
2023-04-13T12:37:14Z
2023-04-13T12:37:14Z 2023-04 |
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Type |
Article
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Identifier |
0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscpr.res.in/handle/123456789/61745 https://doi.org/10.56042/ijtk.v22i1.46266 |
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Language |
en
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Relation |
A61K 36/00
A61K 36/185 A61K 45/06 A61P 1/16 |
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Publisher |
NIScPR-CSIR, India
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Source |
IJTK Vol.22(1) [January 2023]
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