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An open label hepatoprotective activity of Jawārish bisbāsā in central obesity patients

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Title An open label hepatoprotective activity of Jawārish bisbāsā in central obesity patients
 
Creator Azhar, Misbahuddin
Ayub, Sadia
Ansari, Rashidul Islam
Anjum, Nighat
Rej, Anirban
Khan, Asim Ali
 
Subject Clinical validation
Hepatoprotective
Jawārish bisbāsā
Unani medicine
 
Description 57-62
Liver plays a major role in metabolism and excretion of xenobiotics. Liver dysfunction is a major health problem that
challenges health care professionals, pharmaceutical industry and drug regulatory agencies. The most common symptoms
are fatigue and discomfort in abdomen while in patients who are obese with BMI > 25, about one third have metabolic
syndromes. The present clinical research was conducted in Regional Research Institute of Unani Medicine, Aligarh. The
patients under trial were selected from GOPD of institute for obesity and it was observed that out of total registered patients’
approx 28% have elevated liver enzymes from its normal range without any sign and symptom of hepatitis etc. Total 23
patients were selected from the study whose liver enzymes (SGOT, SGPT and ALP) were high at the baseline. Unani
pharmacopoeial drug Jawārish bisbāsā 7 g daily was prescribed with lukewarm water in the morning and evening empty
stomach for 8 weeks. At the end of study the result were compared with base line. It was observed that Jawārish bisbāsā
significantly reduced the liver enzymes, e.g. SGOT, SGPT, Alkaline Phosphatase in comparison to baseline values. It may
be concluded that Jawārish bisbāsā showed hepatoprotective effect in this clinical study.
 
Date 2023-04-17T09:20:30Z
2023-04-17T09:20:30Z
2023-04
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscpr.res.in/handle/123456789/61761
https://doi.org/10.56042/ijtk.v22i1.51840
 
Language en
 
Relation A61K 36/00
A61K 9/00
A61P 1/16
 
Publisher NIScPR-CSIR, India
 
Source IJTK Vol.22(1) [January 2023]