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Biopotential insights and structural chemistry of some zirconocene incorporated heterocyclic β-diketones and flexible N-protected α/β- amino acids

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Title Biopotential insights and structural chemistry of some zirconocene incorporated heterocyclic β-diketones and flexible N-protected α/β- amino acids
 
Creator Sharma, Kanika
Soni, Komal
Saxena, Sanjiv
Jain, Asha
 
Subject Heterocyclic β-diketones
N-protected α/ β-amino acids
Zirconocene complexes
Antimicrobial activity
 
Description 331-338
The interaction of zirconocene dichloride with the heterocyclic β-diketones (LH) and flexible N-protected α/ β-amino
acids (AH) in the presence of triethylamine in 1:1:1:2 molar ratio in refluxing dry THF has been resulted in the formation of
zirconocene complexes of the general formula [ZrCp2(RCOC:C(O)N(C6H5)N:CCH3)(O2CCHR'NC(O)C6H4C(O))](where R= -
CH3, -CH2CH3, p-ClC6H4-, -C6H5 and CHR’ = -CH2CH2and R’ = CH(CH3)2). These newly generated zirconocene
incorporated organic-inorganic hybrid products have been characterized by FTIR, NMR (1H and 13C) and mass
spectrometry. Some of these complexes and their corresponding ligands have been tested for their antimicrobial activity to
examine the biopotential activity-structure relationship.
 
Date 2023-04-17T10:23:06Z
2023-04-17T10:23:06Z
2023-04
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/61776
https://doi.org/10.56042/ijc.v62i4.427
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC Vol.62(04) [Apr 2023]