Biopotential insights and structural chemistry of some zirconocene incorporated heterocyclic β-diketones and flexible N-protected α/β- amino acids
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Title |
Biopotential insights and structural chemistry of some zirconocene incorporated heterocyclic β-diketones and flexible N-protected α/β- amino acids
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Creator |
Sharma, Kanika
Soni, Komal Saxena, Sanjiv Jain, Asha |
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Subject |
Heterocyclic β-diketones
N-protected α/ β-amino acids Zirconocene complexes Antimicrobial activity |
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Description |
331-338
The interaction of zirconocene dichloride with the heterocyclic β-diketones (LH) and flexible N-protected α/ β-amino acids (AH) in the presence of triethylamine in 1:1:1:2 molar ratio in refluxing dry THF has been resulted in the formation of zirconocene complexes of the general formula [ZrCp2(RCOC:C(O)N(C6H5)N:CCH3)(O2CCHR'NC(O)C6H4C(O))](where R= - CH3, -CH2CH3, p-ClC6H4-, -C6H5 and CHR’ = -CH2CH2and R’ = CH(CH3)2). These newly generated zirconocene incorporated organic-inorganic hybrid products have been characterized by FTIR, NMR (1H and 13C) and mass spectrometry. Some of these complexes and their corresponding ligands have been tested for their antimicrobial activity to examine the biopotential activity-structure relationship. |
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Date |
2023-04-17T10:23:06Z
2023-04-17T10:23:06Z 2023-04 |
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Type |
Article
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Identifier |
2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/61776 https://doi.org/10.56042/ijc.v62i4.427 |
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Language |
en
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Publisher |
NIScPR-CSIR, India
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Source |
IJC Vol.62(04) [Apr 2023]
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