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Novel high yielding route for the synthesis of Melphalan dimer impurity G
NOPR - NISCAIR Online Periodicals Repository
View Archive Info| Field | Value | |
| Title |
Novel high yielding route for the synthesis of Melphalan dimer impurity G
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| Creator |
Rane, R A
Male, R D Babhulkar, G V Suryawanshi, M R Kumar, Dileep Chindhe, S Pawar, D Moharir, S R Patil, R K |
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| Subject |
Melphalan
Impurity Synthesis Dimer impurity Antineoplastic agent |
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| Description |
313-317
Melphalan dimer is an impurity from the synthesis of Melphalan (M216900) which is an antineoplastic agent. In this article, a new route for the synthesis of Melphalan dimer impurity G has been discussed. The new research provides the first high-yield, high-purity synthesis of this impurity. The impurity has been confirmed for purity using HPLC, and its structure has been identified using MS, ¹H and ¹³C NMR. |
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| Date |
2023-04-17T10:30:34Z
2023-04-17T10:30:34Z 2023-04 |
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| Type |
Article
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| Identifier |
2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/61779 https://doi.org/10.56042/ijc.v62i4.416 |
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| Language |
en
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| Publisher |
NIScPR-CSIR, India
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| Source |
IJC Vol.62(04) [Apr 2023]
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