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New Insights into the Mechanism of Maternal Recognition of Pregnancy in Ruminants

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Title New Insights into the Mechanism of Maternal Recognition of Pregnancy in Ruminants
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Creator Babu Lal Kumawat, Sanjay Kumar Singh, Manas Kumar Patra, Harendra Kumar, Narayanan Krishnaswamy
 
Subject Bovine reproduction
 
Description Not Available
Maternal recognition of pregnancy (MRP) is an early embryonic event that converts a cyclical corpus luteum (CL) into a pregnancy CL. In the ruminants, MRP is mediated by the conceptus-derived trophoblastic interferon-τ (IFNτ) that inhibits the release of oxytocin (OXT) driven luteolytic pulses of prostaglandin F2α (PGF2α) from the epithelial cells of the endometrium. In parallel, IFNτ stimulates the production of PGE2 from the stromal cells that has luteoprotective effects. This chapter attempts to update the mechanisms by which PGE2 favors MRP and early establishment of pregnancy. Understanding the regulation of the endometrial OXT receptor (OXTR) expression during the late luteal phase of a fertile estrous cycle is an important, but least, understood aspect of MRP.
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Date 2023-05-02T06:06:19Z
2023-05-02T06:06:19Z
2022-06-16
 
Type Book chapter
 
Identifier Kumawat, B.L., Singh, S.K., Patra, M.K., Kumar, H., Krishnaswamy, N. (2022). New Insights into the Mechanism of Maternal Recognition of Pregnancy in Ruminants. In: Kumaresan, A., Srivastava, A.K. (eds) Current Concepts in Bovine Reproduction. Springer, Singapore. https://doi.org/10.1007/978-981-19-0116-4_8
978-981-19-0116-4
http://krishi.icar.gov.in/jspui/handle/123456789/76943
 
Language English
 
Relation Not Available;
 
Publisher Springer Nature Singapore