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Synthesis and antimicrobial activity of novel (1-phenyl-1H-1,2,3-triazo-4-yl) methyl-2-acetamido-1-phenyl-1H-benzo[f]chromene-3-carboxylate and 2-aminooctahydro- 4-phenyl-2H-chromene-3-carbonitrile

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Title Synthesis and antimicrobial activity of novel (1-phenyl-1H-1,2,3-triazo-4-yl) methyl-2-acetamido-1-phenyl-1H-benzo[f]chromene-3-carboxylate and 2-aminooctahydro- 4-phenyl-2H-chromene-3-carbonitrile
 
Creator Shamili, Sriramoju
Siddoju, Kavitha
Chandrakala, G
Farheen, Sd Ishrath
 
Subject -Amino-1H-chromene-2-carbonitriles
Chromenes
Multicomponent reaction
Chloramphenicol
Amphotericin-B
 
Description 445-453
A series of novel (1-phenyl-1H-1,2,3-triazol-4-yl)methyl-2-acetamido-1-phenyl-1H-benzo[f] benzo[f]chromene-3-
carboxylate 6a-i compounds have been synthesised from prop-2-yn-1yl-3-acetamido-1-phenyl-1H-benzo[f]chromene-2-
carboxylate 5. 3-Amino-1-phenyl-1H-benzo[f]chromene-2-carbonitrile and 2-amino-4-phenyl-4a,5,6,7,8,8a-hexahydro-4Hchromene-
3-carbonitrile (1 and 2a) are generated when benzaldehyde, β-naphthol, (or) cyclohexanol, and malononitrile are
incorporated into the mixture. Activity of two conventional antibiotics, Chloramphenicol and Amphotericin-B, have been
compared to the antibacterial and antifungal properties of the prepared synthetic compounds. A study has been conducted on
the spectroscopic properties of Schlenter products
 
Date 2023-05-18T05:30:32Z
2023-05-18T05:30:32Z
2023-05
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/61929
https://doi.org/10.56042/ijc.v62i5.1423
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJC Vol.62(05) [May 2023]