Synthesis and antimicrobial activity of novel (1-phenyl-1H-1,2,3-triazo-4-yl) methyl-2-acetamido-1-phenyl-1H-benzo[f]chromene-3-carboxylate and 2-aminooctahydro- 4-phenyl-2H-chromene-3-carbonitrile
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Title |
Synthesis and antimicrobial activity of novel (1-phenyl-1H-1,2,3-triazo-4-yl) methyl-2-acetamido-1-phenyl-1H-benzo[f]chromene-3-carboxylate and 2-aminooctahydro- 4-phenyl-2H-chromene-3-carbonitrile
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Creator |
Shamili, Sriramoju
Siddoju, Kavitha Chandrakala, G Farheen, Sd Ishrath |
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Subject |
-Amino-1H-chromene-2-carbonitriles
Chromenes Multicomponent reaction Chloramphenicol Amphotericin-B |
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Description |
445-453
A series of novel (1-phenyl-1H-1,2,3-triazol-4-yl)methyl-2-acetamido-1-phenyl-1H-benzo[f] benzo[f]chromene-3- carboxylate 6a-i compounds have been synthesised from prop-2-yn-1yl-3-acetamido-1-phenyl-1H-benzo[f]chromene-2- carboxylate 5. 3-Amino-1-phenyl-1H-benzo[f]chromene-2-carbonitrile and 2-amino-4-phenyl-4a,5,6,7,8,8a-hexahydro-4Hchromene- 3-carbonitrile (1 and 2a) are generated when benzaldehyde, β-naphthol, (or) cyclohexanol, and malononitrile are incorporated into the mixture. Activity of two conventional antibiotics, Chloramphenicol and Amphotericin-B, have been compared to the antibacterial and antifungal properties of the prepared synthetic compounds. A study has been conducted on the spectroscopic properties of Schlenter products |
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Date |
2023-05-18T05:30:32Z
2023-05-18T05:30:32Z 2023-05 |
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Type |
Article
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Identifier |
2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/61929 https://doi.org/10.56042/ijc.v62i5.1423 |
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Language |
en
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Publisher |
NIScPR-CSIR,India
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Source |
IJC Vol.62(05) [May 2023]
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