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The domesticated buffalo - An emerging model for experimental and therapeutic use of extraembryonic tissues.

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Title The domesticated buffalo - An emerging model for experimental and therapeutic use of extraembryonic tissues.
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Creator Singh B, Mal G, Kues, W.A. and Yadav, P.S.
 
Subject Bubalus bubalis Animal model Placenta Amnion Chorion Cell therapy Cellular reprogramming
 
Description Not Available
Large animals play important roles as model animals for biomedical sciences and translational research.
The water buffalo (Bubalus bubalis) is an economically important, multipurpose livestock species.
Important assisted reproduction techniques, such as in vitro fertilization, cryo-conservation of sperm and
embryos, embryo transfer, somatic cell nuclear transfer, genetic engineering, and genome editing have
been successfully applied to buffaloes. Recently, detailed whole genome data and transcriptome maps
have been generated. In addition, rapid progress has been made in stem cell biology of the buffalo. Apart
from embryonic stem cells, bubaline extra-embryonic stem cells have gained particular interest. The
multipotency of non-embryonic stem cells has been revealed, and their utility in basic and applied
research is currently investigated. In particular, success achieved in bubaline extra-embryonic stem cells
may have important roles in experimental biology and therapeutic regenerative medicine. Progress in
other farm animals in assisted reproduction techniques, stem cell biology and genetic engineering, which
could be of importance for buffalo, will also be briefly summarized.
Not Available
 
Date 2023-05-24T08:17:19Z
2023-05-24T08:17:19Z
2020-01-01
 
Type Review Paper
 
Identifier Not Available
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http://krishi.icar.gov.in/jspui/handle/123456789/77724
 
Language English
 
Relation Not Available;
 
Publisher Not Available