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Gastrointestinal biotransformation of phytochemicals: Towards futuristic dietary therapeutics and functional foods.

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Title Gastrointestinal biotransformation of phytochemicals: Towards futuristic dietary therapeutics and functional foods.
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Creator Singh B, Mal G, Sharma D, Sharma R, Antony CP, Kalra RS.
 
Subject Gut microbiome Phytochemicals Colon biotransformation Functional food Nutrition Dietary therapeutics
 
Description Not Available
Background: Gastrointestinal (GI) microbiome is a highly diverse and intricate symbiotic ecosystem that offers a
multitude of metabolic and adaptive benefits to the host. Diverse phytochemicals consumed as vegetarian diet or
taken as food supplements are metabolized intensely in the GI tract and provide a range of nutritional and dietary
therapeutic benefits. Insights into the gut microbial-biotransformation and plant-based therapeutics with refer ence to the diet and their interaction with the host offers development of futuristic dietary therapeutics that
could boost the efficacy of nutraceuticals and plant-based formulations for human health.
Scope and approach: This review provides insights into the gut microbial biotransformation of selective pre dominant dietary phytochemicals and the biological activities of the produced metabolites. It emphasizes the
potential of GI microbes as probiotics or microbial food additives to improve utilization of plant-based diets, and
enhance the bioavailability and bioactivities of phytochemicals.
Key findings and conclusions: Vital and pro-health activities of plant metabolites produced as a result of gut mi crobial biotransformation emphasize the use of gut microbiota as novel probiotic candidates. The inferences
summed up in the report could pave the way to develop potential probiotics to increase the efficiency of plant based therapeutics towards enabling human hosts to cope with metabolic, inflammatory, proliferative, infectious
and non-infectious diseases. We believe that the obtained and acquired new knowledge as discussed here has
implications to develop dietary therapeutics that could steer the functioning of gut microbiota towards boosting
host’s nutritional and immunomodulatory efficiency.
Not Available
 
Date 2023-05-24T08:22:23Z
2023-05-24T08:22:23Z
2020-01-01
 
Type Review Paper
 
Identifier Not Available
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/77733
 
Language English
 
Relation Not Available;
 
Publisher Not Available