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Assessment of the relationship between serum neutralizing antibody titre and liquid phase blocking ELISA titre in immune response to FMDV Vaccine

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Title Assessment of the relationship between serum neutralizing antibody titre and liquid phase blocking ELISA titre in immune response to FMDV Vaccine
Not Available
 
Creator R P Tamil Selvan
B P Sreenivasa
M Hosamani
P Saravanan
S H Basagoudanavar
R Venkataramanan
 
Subject FMD vaccine
LPBE
serum neutralization test
 
Description Not Available
Traditionally, quality assessment of FMD vaccine is carried out by live FMD virus challenge of vaccinated cattle. Replacing the use of animals for quality assessment with in vitro tests like serum neutralization test (SNT) or liquid phase blocking ELISA (LPBE), requires the establishment of logistic regression models from series of challenge experiments. Before establishing a logistic regression model, we did a preliminary investigation on the relationship between SNT and LPBE titre, to be used as cut-off titre for classifying cattle as protected or unprotected.
Not Available
 
Date 2023-05-30T09:20:19Z
2023-05-30T09:20:19Z
2016-05-01
 
Type News Letter
 
Identifier Not Available
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/77913
 
Language English
 
Relation issue no 5;
 
Publisher Global Foot-and-mouth disease Research Alliance (GFRA) Newsletter