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Plant - based antibiotic adjuvants - A roadmap to combat antibiotic resistance.

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Title Plant - based antibiotic adjuvants - A roadmap to combat antibiotic resistance.
Not Available
 
Creator Jairath, G.
Gopinath, D.
Rialch, A.
Mal, G.
Singh, B.
Sharma, R.
 
Subject antibiotic adjuvants, multidrug resistance
 
Description Not Available
Multidrug-resistant bacteria have now emerged as a global threat
due to the emergence of new or re-emergence of old pathogens.
This alarming situation demands either to find new/modified
effective antibiotics or alternatives to reduce the overall load of
infectious diseases both in the veterinary and public domain.
Antibiotic adjuvants are non-antibiotic compounds that potentiate
the existing antibiotic activity. The Himalayan region being a big
basket and hot spot of biodiversity, inhabiting a diverse flora of
medicinal plants/herbs can be evaluated for antibiotic adjuvants.
These adjuvants work either by blocking the main bacterial
resistance mechanisms or enhancing the antimicrobial action of

the drug. The adjuvants assist in polypharmacy on bacteria by de-
energizing the efflux pump channel of bacteria to escape

antibiotic action and by allowing antibiotics to have greater
internal access. Thus, the plant-based antibiotic adjuvants have
the potency to re-empower the existing antibiotics, restoring their
activities against target pathogen that too with minimal side
effects/toxicity being natural in origin.
Not Available
 
Date 2023-05-31T06:09:05Z
2023-05-31T06:09:05Z
2021-12-01
 
Type Magazine
 
Identifier Jairath, G., Gopinath, D., Rialch, A., Mal, G., Singh, B. and Sharma, R. (2021). Plant - based antibiotic adjuvants - A roadmap to combat antibiotic resistance. AgroScience Today, 2 (12): 0303-0305.
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/77930
 
Language English
 
Relation Not Available;
 
Publisher Cornous Publisher