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Design and application of a new julolidine-based photolabile protecting group

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Field Value
 
Title Design and application of a new julolidine-based photolabile protecting group
 
Creator Sama, Gopal Reddy
 
Subject Benzyl type PPGs
Julolidine-based PPG
Mild condition
Deprotection
 
Description 662-672
Photolabile protecting groups (PPGs) are invaluable tools for protecting a variety of functionalities and serve as
alternatives to protecting groups that need chemical cleavage. PPGs are mainly classified into 3 categories namely,
2-nitrobenzyl type PPGs, coumarin-based PPGs, and benzyl type PPGs which have been designed by Wang and co-workers
based on the meta effect and computational study observations. This work describes the design and synthesis of a julolidinebased
benzyl type PPG 4 and the analysis of its reaction intermediates. The julolidine PPG 4 is applied for the protection of
alcohols as carbonates, amines as carbamates, carboxylic acids as esters, and hydroxamic acid. Analysis of the photolyzed
samples by HPLC has also been conducted.
 
Date 2023-06-15T06:08:28Z
2023-06-15T06:08:28Z
2023-06
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/62027
https://doi.org/10.56042/ijc.v62i6.2570
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC Vol.62(06) [June 2023]