Design and application of a new julolidine-based photolabile protecting group
NOPR - NISCAIR Online Periodicals Repository
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Title |
Design and application of a new julolidine-based photolabile protecting group
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Creator |
Sama, Gopal Reddy
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Subject |
Benzyl type PPGs
Julolidine-based PPG Mild condition Deprotection |
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Description |
662-672
Photolabile protecting groups (PPGs) are invaluable tools for protecting a variety of functionalities and serve as alternatives to protecting groups that need chemical cleavage. PPGs are mainly classified into 3 categories namely, 2-nitrobenzyl type PPGs, coumarin-based PPGs, and benzyl type PPGs which have been designed by Wang and co-workers based on the meta effect and computational study observations. This work describes the design and synthesis of a julolidinebased benzyl type PPG 4 and the analysis of its reaction intermediates. The julolidine PPG 4 is applied for the protection of alcohols as carbonates, amines as carbamates, carboxylic acids as esters, and hydroxamic acid. Analysis of the photolyzed samples by HPLC has also been conducted. |
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Date |
2023-06-15T06:08:28Z
2023-06-15T06:08:28Z 2023-06 |
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Type |
Article
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Identifier |
2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/62027 https://doi.org/10.56042/ijc.v62i6.2570 |
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Language |
en
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Publisher |
NIScPR-CSIR, India
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Source |
IJC Vol.62(06) [June 2023]
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