Preparation of nanofibrous mat using eco-friendly, biocompatible and biodegradable material
NOPR - NISCAIR Online Periodicals Repository
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Title |
Preparation of nanofibrous mat using eco-friendly, biocompatible and biodegradable material
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Creator |
Razaghpour, Mojgan
Moazzenchi, Bahareh Pourhosseini, Farhad Mongkholrattanasit, Rattanaphol |
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Subject |
Antibacterial properties
Biocompatible fibre Biodegradable fibre Chitosan Mechanical properties Nanofibrous Pectin Polyvinyl alcohol |
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Description |
181-189
A novel blend of pectin/ chitosan (CS)/polyvinyl alcohol (PVA)has been prepared as a nanofibrous scaffold for skin tissue engineering and wound healing applications. Pectin has been used as an eco-friendly, non-toxic and watersoluble polymer to improve nanofibre properties. Pectin as a poly-anion polymer, in combination with chitosan polycationic polymers, creates a cross-linked poly-electrolyte complex with biocompatible properties. The CS/PVA solutions containing various concentrations of pectin are electrospun to form a 3D pectin/ CS/ PVA nano fibrous scaffold. Mechanical and antibacterial properties of the nanofibrous scaffolds are evaluated by various instrumental techniques, such as Attenuated Total Reflection-Fourier Transform Infrared, Scanning Electron Microscopy, nitrogen content and Differential Scanning Calorimetry. Mechanical properties are found to be improved and the strong antibacterial activity of the pectin/CS/PVA nano fibrous scaffold is confirmed against Escherichia coli, Staphylococcus aureus, Klebsiella and Candida albicans. |
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Date |
2023-06-27T09:06:10Z
2023-06-27T09:06:10Z 2023-06 |
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Type |
Article
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Identifier |
0975-1025 (Online); 0971-0426 (Print)
http://nopr.niscpr.res.in/handle/123456789/62092 https://doi.org/10.56042/ijftr.v48i2.52781 |
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Language |
en
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Publisher |
NIScPR-CSIR, India
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Source |
IJFTR Vol.48(2) [June 2023]
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