Effect of external washing with self-made Xiaofeng Jiedu powder on expressions of serum inflammatory cytokines in patients with cutaneous adverse events induced by programmed cell death protein 1 inhibitor
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Title |
Effect of external washing with self-made Xiaofeng Jiedu powder on expressions of serum inflammatory cytokines in patients with cutaneous adverse events induced by programmed cell death protein 1 inhibitor
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Creator |
Guo, Junhua
Chen, Wen Hu, Keke Jiang, Lu |
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Subject |
PD-1 inhibitor
Traditional Chinese medicine Tumor |
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Description |
578-584
Wide application of programmed cell death protein 1 (PD-1) inhibitor for tumor treatment has led to increased immune-related adverse events (irAEs), particularly cutaneous irAE. In this study, we assessed the effects of external washing with self-made Xiaofeng Jiedu powder on the expressions of serum inflammatory cytokines in patients with cutaneous adverse events (AEs) induced by PD-1 inhibitor. Fifty-six tumor patients with cutaneous AEs induced by PD-1 inhibitor were randomly divided into observation and control groups (n=28). The control group underwent routine treatment with PD-1 inhibitor and oral administration with cetirizine, while the observation group received PD-1 inhibitor and soaking and fumigation by Xiaofeng Jiedu powder in the affected skin once in the morning and once in the evening. The levels of serum interleukin-6 (IL-6), IL-10, and immunoglobulin E (IgE) were detected before and after treatment. After treatment, the disease control rate of the observation group was higher than that of the control group (P |
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Date |
2023-06-28T09:51:00Z
2023-06-28T09:51:00Z 2023-07 |
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Type |
Article
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Identifier |
0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/62127 https://doi.org/10.56042/ijeb.v61i07.2464 |
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Language |
en
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Publisher |
NIScPR-CSIR, India
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Source |
IJEB Vol.61(07) [July 2023]
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