Record Details

Effect of exogenous pulmonary surfactant on infectious pneumonia, serum procalcitonin, high-sensitivity C-reactive protein and interleukin-6 in neonates

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Effect of exogenous pulmonary surfactant on infectious pneumonia, serum procalcitonin, high-sensitivity C-reactive protein and interleukin-6 in neonates
 
Creator Jia, Dezhao
Tu, Xiaoqiong
 
Subject Antithrombin
Blood gas indices
Inflammatory factors
Neonatal infectious pneumonia
Oxygenation status
 
Description 573-577
Infectious pneumonia common among neonates has morbidity rate as high as 25%. Proper clinical diagnosis with treatment for respiratory and circulatory failure may prevent mortality. Neonates with infectious pneumonia are mostly treated with mechanical ventilation, antibiotics and pulmonary surfactant. Here, we assessed the effects of exogenous pulmonary surfactant on neonatal infectious pneumonia (NIP). A total of 120 neonates treated from October 2019 to December 2020 were randomly divided into control and observation groups (n=60). Control group received conventional treatment for 7 d, based on which observation group was given 100 mg/kg PS. Their blood gas indices, oxygenation status, lung consolidation and levels of serum procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6) were compared. Partial pressure of oxygen (PaO2) increased, while that of carbon dioxide (PaCO2) decreased 24 and 48 h after treatment compared with those before treatment, and the observation group had higher PaO2 and lower PaCO2 (P
 
Date 2023-06-28T09:53:45Z
2023-06-28T09:53:45Z
2023-07
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/62128
https://doi.org/10.56042/ijeb.v61i07.3117
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJEB Vol.61(07) [July 2023]