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Studies on standardization and purification processes of VEERAM

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Title Studies on standardization and purification processes of VEERAM
 
Creator R, Madhavan
J, Muthukumar N
C, Savariraj Sagayam
P, Rajalakshmi
P, Brindha
 
Subject Geochemical
Instrumentation techniques
Physico-chemical analysis
Veeram
 
Description 330-339
In Siddha system of medicine Veeram is one of the toxins among the sixty four known toxins. Geologically it is called
Calomel. It is a very toxic material therapeutically, these arsenic based medicines are used in Siddha system. Natural substances
of milk, tender coconut water, bitter guard and lemon juice are used to purify the veeram. This research work analyzed the raw
veeram and products obtained after purification. Geochemical, physico-chemical analysis, instrumentation techniques of XRF,
TG-DTA, FE-SEM, EDAX and particle size analyzer. Among physicochemical parameters total ash value was low. Loss on
drying increased in the products in the various intermediate stages which due to the impact of plant agents used in the process.
XRF results revealed mercury is present in major concentration. Raw veeram showed 77.14% of mercury. In the raw veeram
particles observed were distributed within the range of 0.0920 μm–0.948 μm. FE-SEM analysis suggested that the bitter gourd
treated veeram consisted of individual particles with a size ranging from 94 nm to 144 nm. Milk treated samples when subjected
to analysis revealed increased particle size which may be attributed to aggregation. Lemon juice treated samples showed
particle size in the range of 82 nm to 96 nm and in tender coconut range was 78 nm to 91 nm. In the EDAX raw and other
samples showed peak for mercury and chloride. TG-DTA analysis showed that the raw veeram sample had a sublimation
temperature of 220C where as in other treated samples sublimation temperature was reduced compared to raw veeram. The
from the stydy depict that these purification processes forms new organic substances and transformation of the starting toxic
metal. These processes have an important role in the formation of complexes and in altering toxic state to non-toxic state.
 
Date 2023-06-28T11:56:47Z
2023-06-28T11:56:47Z
2023-06
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscpr.res.in/handle/123456789/62181
https://doi.org/10.56042/ijtk.v22i2.31777
 
Language en
 
Relation Int Cl.23: A61K 31/285, A61K 36/00, A62K 36/185
 
Publisher NIScPR-CSIR,India
 
Source IJTK Vol.22(2) [April 2023]