From synthesis to bioactivity: A comprehensive study of Cu-based biocidal tool
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Title |
From synthesis to bioactivity: A comprehensive study of Cu-based biocidal tool
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Creator |
Krishna, N Anantha
Reddy, Y V Mohana Reddy, B Chandra Mohan |
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Subject |
Biocidal, Copper
Fermentation Metallurgy Organic Rasa shastra |
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Description |
322-329
The present study reports on the biogenic synthesis of a copper-based biocidal material through the fermentation of gruel, a traditional non-alcoholic beverage. This process may involve a bio-beneficiation mechanism, in which the indigenous microorganisms in the ferment interact with the material. X-ray diffraction analysis confirmed the powder's crystalline copper composition. Fourier-transform infrared spectroscopy revealed the crucial role of organic acids in the capping process. Transmission electron microscopy, ultraviolet-visible spectroscopy, and antimicrobial susceptibility tests were conducted to characterize the powder. Furthermore, the biocidal material was combined with the anticancer drug curcumin to explore its additional anti-proliferative effects, including apoptosis, on human hepatocellular carcinoma cell lines in vitro. These findings highlight the potential of this biogenic copper material as a promising candidate for biomedical applications. |
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Date |
2023-06-28T12:06:55Z
2023-06-28T12:06:55Z 2023-06 |
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Type |
Article
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Identifier |
0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscpr.res.in/handle/123456789/62182 https://doi.org/10.56042/ijtk.v22i2.33940 |
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Language |
en
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Relation |
Int Cl.23: A01N 59/20
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Publisher |
NIScPR-CSIR,India
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Source |
IJTK Vol.22(2) [April 2023]
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