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From synthesis to bioactivity: A comprehensive study of Cu-based biocidal tool

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Field Value
 
Title From synthesis to bioactivity: A comprehensive study of Cu-based biocidal tool
 
Creator Krishna, N Anantha
Reddy, Y V Mohana
Reddy, B Chandra Mohan
 
Subject Biocidal, Copper
Fermentation
Metallurgy
Organic
Rasa shastra
 
Description 322-329
The present study reports on the biogenic synthesis of a copper-based biocidal material through the fermentation of gruel,
a traditional non-alcoholic beverage. This process may involve a bio-beneficiation mechanism, in which the indigenous
microorganisms in the ferment interact with the material. X-ray diffraction analysis confirmed the powder's crystalline
copper composition. Fourier-transform infrared spectroscopy revealed the crucial role of organic acids in the capping
process. Transmission electron microscopy, ultraviolet-visible spectroscopy, and antimicrobial susceptibility tests were
conducted to characterize the powder. Furthermore, the biocidal material was combined with the anticancer drug curcumin
to explore its additional anti-proliferative effects, including apoptosis, on human hepatocellular carcinoma cell lines in vitro.
These findings highlight the potential of this biogenic copper material as a promising candidate for biomedical applications.
 
Date 2023-06-28T12:06:55Z
2023-06-28T12:06:55Z
2023-06
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscpr.res.in/handle/123456789/62182
https://doi.org/10.56042/ijtk.v22i2.33940
 
Language en
 
Relation Int Cl.23: A01N 59/20
 
Publisher NIScPR-CSIR,India
 
Source IJTK Vol.22(2) [April 2023]