Serum triacylglycerol: A putative early biomarker of disease severity of Type 2 diabetes mellitus compared to microalbuminuria
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Title |
Serum triacylglycerol: A putative early biomarker of disease severity of Type 2 diabetes mellitus compared to microalbuminuria
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Creator |
Sarma, Nibedita
Dawn, Somali Dhar, Aninda Chatterjee, Namrata Hadem, Ibanylla Kyanjai Hynniewta Asmita Hazra, Asmita Pal, Amit Sahoo, Sibasish Dutta, Atanu Kumar Goswami, Kalyan Saha |
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Subject |
Diabetic nephropathy
Glycaemia, HbA1c Hyperglycemia Hypertriglyceridemia Post prandial plasma glucose Receiver operating characteristic curve |
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Description |
499-504
Poorly controlled type 2 diabetes mellitus progresses to several complications including nephropathy. While glycated hemoglobin demarcates severity, urinary microalbumin indicates renal involvement. Considering nephropathy is a late manifestation of the disease, here, we explored whether serum triacylglycerol (TAG) can be used as an early disease severity biomarker. About 100 Type 2 diabetes mellitus patients were recruited and categorized as moderate (n=43) and severe (n=57) based on glycated haemoglobin (8%) level. Duration of the disease, BMI, systolic and diastolic BP, fasting and Post Prandial plasma glucose, glycated haemoglobin, serum lipid profile and urinary microalbumin were measured. Results obtained were compared between the groups and correlated. Taking glycated haemoglobin as reference, receiver operating characteristic curves were constructed for serum triacylglycerol and urinary microalbumin excretion to check their efficacy as classifier of disease severity. Significant differences (P |
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Date |
2023-06-30T05:58:40Z
2023-06-30T05:58:40Z 2023-06 |
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Type |
Article
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Identifier |
0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/62218 https://doi.org/10.56042/ijeb.v61i07.2214 |
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Language |
en
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Publisher |
NIScPR-CSIR, India
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Source |
IJEB Vol.61(07) [July 2023]
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