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From error to uncertainty: A search for variabilities in the laboratory reports

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Field Value
 
Title From error to uncertainty: A search for variabilities in the laboratory reports
 
Creator Goswami, Kalyan
Sahoo, Sibasish
Mukhopadhyay, Kaushik
 
Subject Bias
Errors
Total error
True error
Uncertainty
 
Description 479-484
With the advancement of science and technology the diagnostic modality has been gradually getting integrated with the
health care, thereby evolving into a new discipline of lab medicine. Therefore, the role of lab is no more limited to analytical
phase only but expanded to clinical decision making and management planning. This demanded better quality assurance in
lab reporting. The advent of sophisticated technology in clinical biochemistry lab, the error in analytical phase is drastically
reduced, However, the preanalytical including biological variations has emerged as the major source of variations in the lab
report. Therefore, definite need has been felt to think beyond the total error paradigm of lab quality control, resulting into
the concept of uncertainty which can accommodate all possible components of the lab medicine as a probable source of
uncertainty in the lab result. The knowledge and implication of the measurement of uncertainty seems to be challenging for
the lab professional as well as the clinicians due to apparent complexity of the statistical methods involved and also for the
lack of accessibility and orientation regarding the requisite computer applications. The regulatory guidelines are endorsing
uncertainty measurement. Hence, it might be imperative to embrace this system in near future.
 
Date 2023-06-30T06:02:57Z
2023-06-30T06:02:57Z
2023-06
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/62221
https://doi.org/10.56042/ijeb.v61i07.2284
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJEB Vol.61(07) [July 2023]