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Synthesis and antituberculosis action of symmetric acridin-9-yl-bisbenzothiazol- 2-yl-amines

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Title Synthesis and antituberculosis action of symmetric acridin-9-yl-bisbenzothiazol- 2-yl-amines
 
Creator Kawle, Pravin R
 
Subject Tuberculosis
Acridine
Benzothiazole
 
Description 691-695
A new series of symmetric acridin-9-yl-bis-benzothiazol-2-yl-amines have been synthesized in good to excellent yields
by intra-molecular cyclization of 1-acridin-9-yl-1-benzothiazol-2-yl-3-aryl thiourea and screened for their in vitro
antitubercular activity against Mycobacterium tuberculosis by BACTEC radiometric method. The synthesis of new
analogues bearing an acridine-linked chloro-substituted benzothiazole has demonstrated enhanced antituberculosis activity.
 
Date 2023-07-20T09:13:42Z
2023-07-20T09:13:42Z
2023-07
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/62320
https://doi.org/10.56042/ijc.v62i7.430
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJC Vol.62(07) [July 2023]