Utility of risk prediction nomogram for lymph node metastasis in the elderly with undifferentiated early gastric cancer
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Title |
Utility of risk prediction nomogram for lymph node metastasis in the elderly with undifferentiated early gastric cancer
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Creator |
Zhang, Yajun
Yin, Tiansheng Liu, Yang Xiao, Jiajun |
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Subject |
Elderly
Harrell concordance index (C-index) Lymph node metastasis Stomach cancer |
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Description |
654-658
Gastric cancer (also called stomach cancer) is the 5th most common cancer the human population suffer from, particularly in East Asia. For effective prevention, it is important to find biomarkers for early-stage diagnosis and prognosis. Further, finding the risk factors that are associated with undifferentiated early gastric cancer is the utmost required. Here, we explored the clinicopathological characteristics of undifferentiated early gastric cancer (EGC) in the elderly, and the risk factors for lymph node metastasis. A total of 187 elderly patients with undifferentiated EGC were selected as subjects, whose clinical data were analyzed retrospectively. They were divided into lymph node metastasis and non-lymph node metastasis groups, and the risk factors for lymph node metastasis were analyzed by univariate and multivariate logistic regression analyses. A nomogram model was established to predict the risk of lymph node metastasis, and then validated. Lymph node metastasis was detected in 32 (17.11%) of the 187 cases. Univariate analysis showed that tumor diameter, depth of invasion, vascular tumor thrombus and local ulcer affected lymph node metastasis (P 2 cm, invasion to submucosa, vascular tumor thrombus and local ulcer were independent risk factors (P 2 cm, invasion to submucosa, vascular tumor thrombus and local ulcer are independent risk factors. |
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Date |
2023-07-31T09:51:09Z
2023-07-31T09:51:09Z 2023-07 |
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Type |
Article
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Identifier |
0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/62377 https://doi.org/10.56042/ijeb.v61i08.4376 |
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Language |
en
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Publisher |
NIScPR-CSIR,India
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Source |
IJEB Vol.61(08) [August 2023]
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