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Utility of risk prediction nomogram for lymph node metastasis in the elderly with undifferentiated early gastric cancer

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Title Utility of risk prediction nomogram for lymph node metastasis in the elderly with undifferentiated early gastric cancer
 
Creator Zhang, Yajun
Yin, Tiansheng
Liu, Yang
Xiao, Jiajun
 
Subject Elderly
Harrell concordance index (C-index)
Lymph node metastasis
Stomach cancer
 
Description 654-658
Gastric cancer (also called stomach cancer) is the 5th most
common cancer the human population suffer from, particularly in
East Asia. For effective prevention, it is important to find
biomarkers for early-stage diagnosis and prognosis. Further,
finding the risk factors that are associated with undifferentiated
early gastric cancer is the utmost required. Here, we explored the
clinicopathological characteristics of undifferentiated early gastric
cancer (EGC) in the elderly, and the risk factors for lymph node
metastasis. A total of 187 elderly patients with undifferentiated
EGC were selected as subjects, whose clinical data were analyzed
retrospectively. They were divided into lymph node metastasis
and non-lymph node metastasis groups, and the risk factors for
lymph node metastasis were analyzed by univariate and
multivariate logistic regression analyses. A nomogram model was
established to predict the risk of lymph node metastasis, and then
validated. Lymph node metastasis was detected in 32 (17.11%) of
the 187 cases. Univariate analysis showed that tumor diameter,
depth of invasion, vascular tumor thrombus and local ulcer
affected lymph node metastasis (P 2 cm, invasion
to submucosa, vascular tumor thrombus and local ulcer were
independent risk factors (P 2 cm, invasion to submucosa, vascular tumor
thrombus and local ulcer are independent risk factors.
 
Date 2023-07-31T09:51:09Z
2023-07-31T09:51:09Z
2023-07
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/62377
https://doi.org/10.56042/ijeb.v61i08.4376
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJEB Vol.61(08) [August 2023]