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Antineoplastic potential of Trichosanthes dioica Root: A treatise

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Title Antineoplastic potential of Trichosanthes dioica Root: A treatise
 
Creator Bhattacharya, Sanjib
 
Subject Antitumor
Chemoprevention
Mitotic index
Oxidative stress
Trichosanthes dioica
 
Description 202-209
Medicinal plants have duly been implicated in the development of typical antineoplastic agents. Here, the medicinal plant
under discourse, Trichosanthes dioica Roxb., commonly known as Pointed gourd in English, Potol in Bengali, is a climber
vine found wild and cultivated all over the plains of India and its neighbouring countries for its fruits, consumed as a
favoured vegetable. The present work attempts to assemble and critically assess the literature outcome of the antineoplastic
potential of T. dioica root. The antineoplastic effects involved cytotoxic, antimitotic, antitumor and cancer chemopreventive
potential of its root - mediated through multifaceted mechanisms. The cytotoxic, antimitoitic and antioxidant effects together
may furnish the mechanistic grounds for its reported antitumor and cancer chemopreventive activities. Further studies on
T. dioica root in this direction, may afford newer effective antitumor leads/drugs from this plant part.
 
Date 2023-07-31T10:20:12Z
2023-07-31T10:20:12Z
2023-07
 
Type Article
 
Identifier 0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscpr.res.in/handle/123456789/62391
https://doi.org/10.56042/ijnpr.v14i2.1161
 
Language en
 
Relation A61K 36/00, A61K 36/42, A61P 35/00
 
Publisher NIScPR-CSIR, India
 
Source IJNPR Vol.14(2) [June 2023]