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Aesculus indica: An ethnomedicinal, phytochemical, and pharmacological review

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Title Aesculus indica: An ethnomedicinal, phytochemical, and pharmacological review
 
Creator Madhvi, Som Kailash
Iqbal, Javaid
Younis, Mohd
 
Subject Aesculus indica
Ethnomedicinal
Pharmacology
Phytochemicals
Sapindaceae
 
Description 174-184
Aesculus indica, commonly known as Indian horse chestnut, is an indigenous tree of the family Sapindaceae, distributed in Nepal, India, Pakistan, and Afghanistan. As an ethnomedicine, its seeds are used to cure jaundice, chest diseases, stomach and joint pain, roots for leucorrhea, and bark for fever and anaemia. The phytochemicals of class phenolic, triterpenoid, glycoside, saponin, and fatty acid have been identified from their different parts and various biological activities such as antioxidant, anti-diabetic, hypocholesterolemic, hypoglycaemic, anti-nociceptive, anti-inflammatory, neuro-depressive, spasmolytic, immunomodulatory, anticancer, enzyme inhibitory, antimicrobial and insecticidal have been reported, which reflected its medicinal importance. However, most biological activities are on the extracts or fractions and need more in-depth study. Therefore, further research is required on the isolation, identification, and characterization of active phytochemicals from the extracts with their mechanism of pharmacological action and detailed toxicological evaluation. In this review, we aim to provide all information regarding traditional uses, morphology, phytochemistry, pharmacology, and toxicity of A. indica and address the research gaps; therefore, will provide a source of information to the researchers for further studies.
 
Date 2023-07-31T10:28:04Z
2023-07-31T10:28:04Z
2023-07
 
Type Article
 
Identifier 0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscpr.res.in/handle/123456789/62393
https://doi.org/10.56042/ijnpr.v14i2.4203
 
Language en
 
Relation A61K 36/00, A61K 36/77, A61P
 
Publisher NIScPR-CSIR, India
 
Source IJNPR Vol.14(2) [June 2023]