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Therapeutic efficacy of chicken egg yolk immunoglobulins against hydropericardium syndrome in broiler chickens

Indian Agricultural Research Journals

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Title Therapeutic efficacy of chicken egg yolk immunoglobulins against hydropericardium syndrome in broiler chickens
 
Creator RANI, V
KUMAR, R
UPADHYAY, A K
KUMAR, M
 
Subject Egg yolk antibodies; FAV-4; Hydropericardium syndrome; Immunoglobulin therapy
 
Description The aim of the present study was to assess the role of passive immunization using Immunoglobulins derived from chicken egg yolk in protection against Hydropericardium syndrome (HPS) in broilers. Immunoglobulins against HPS virus were produced by egg yolk technology. Three methods viz., Dextran sulphate, Polyethylene glycol and Ammonium sulphate method were compared to purify IgY from egg yolk. AGPT and RID were used for confirmation and quantitation of IgY against HPS virus, respectively. ELISA was used to compare IgY titers in serum and yolk samples at different time intervals. IgY titre in yolk at 14, 21, 28 and 56 days PIm was more than that in serum, however peak titer in egg yolk was at 49 days PIm. Administration of IgY to experimentally infected broiler chickens afforded 86.66% protection. These findings demonstrate that IgY obtained from hens immunized by HPS virus could provide an alternative approach for treatment of Hydropericardium syndrome in broilers.
 
Publisher Directorate of Knowledge Management in Agriculture
 
Contributor —
 
Date 2012-06-05
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
—
 
Format application/pdf
 
Identifier http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/18888
 
Source The Indian Journal of Animal Sciences; Vol 82, No 6 (2012)
0367-8318
 
Language eng
 
Relation http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/18888/9241
 
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