Record Details

Toxicopathogenic effect of hexavalent chromium (VI) in chickens

Indian Agricultural Research Journals

View Archive Info
 
 
Field Value
 
Title Toxicopathogenic effect of hexavalent chromium (VI) in chickens
 
Creator Islam, Mizanul
Bhowmik, M K
 
Subject Chickens; Chromium; Toxicopathalogy
 
Description The toxicopathogenic effect of hexavalent chromium was determined in broiler chickens by oral administration of one-tenth of acute lethal dose50, (ALD50) ofchromium oxide (17.2 mg/kg bw) daily for 6 weeks. Clinical signs of toxicity developed from 3 week post-treatment, consisting of gastrointestitlal disturbances and loss of body weight without any morlality in all treatment birds. There were significant decrease in plasma protein and cholesterol and increase in serum transaminase, alkaline and acid phosphatase activities of treated birds. Toxicity had induced moderate to severe pathomorphological changes. suggestive of toxic hepatitis and nephrosis, varying degrees of necrosis and/or depletion of lymphoid cells in the spleen and bursa of Fabricius with presence, of multinucleated giant cells. Liver contained the largest residues of chromium, followed by kidneys, intestine, spleen, brain, heart and lowest in skeletal muscles. The intensity of pathomorphological changes was proportional to the accumulated amount of chromium in tissues/organs.
 
Publisher Directorate of Knowledge Management in Agriculture
 
Date 2005-09-05
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
—
 
Format application/pdf
 
Identifier http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/9415
 
Source The Indian Journal of Animal Sciences; Vol 75, No 9 (2005)
0367-8318
 
Language eng
 
Relation http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/9415/4150
 
Rights Copyright (c) 2014 The Indian Journal of Animal Sciences