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Haematologieal and biochemical responses in native sheep experimentally infected dth bluetongue Grus serotype-23

Indian Agricultural Research Journals

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Title Haematologieal and biochemical responses in native sheep experimentally infected dth bluetongue Grus serotype-23
 
Creator SINGH, K P
CHANNAKESRAVA, S U
AHMED, K A
PANDEY, A B
 
Subject BTV-23 seryotype; Haematology; Serum biochemistry; Sheep; Tissue damage
 
Description Haematological and sero-biochemical responses of sero-negative native sheep to bluetongue virus serotype-23 were studied and compared with the control group. Two test groups, each containing 8 animals were inoculated with 6xIOSF TCID,, of BTV-23 serotype separately by intravenous (GrIV) and intradermal (GrID) routes. The blood and serum samples were analyzed at 0, 3, 7, 11, 15 and 20 days post-infection (DPI). Significant changes were observed in all the hematological and biochemical parameters studied. Marked leucopenia was observed on 3 DPI in GrID while leucocytosis in GrIV group. Significant leucocytosis was observed during 11 to 15 DPI in both the infected groups. Significant thrombocytopenia was observed during 3 to 15 DPI whereas significantly low PCV and Hb values were observed between 3 and 11 DPI in both test groups. Differential leucocytes count revealed significantly low lymphocyte percentage on day 3 and high on day 15 in both the infected groups. Under enzyme biochemical studies, ALT registered significantly high values during 7 to 20 DPI in both the test groups, AST during 11 DPI in GrIV and 7 to 11 DPI in GrID, ALP during 3 to 11 DPI in GrIV and 7 DPI in GrID, and CK during 7 to 15 DBI in both the test groups. These findings indicated the damage to various soft tissue organs and muscles as a sequel to vascular endothelial damage and subsequent inflammatory changes with associated ischemia and necrosis
 
Publisher Directorate of Knowledge Management in Agriculture
 
Contributor —
 
Date 2011-01-11
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
—
 
Format application/pdf
 
Identifier http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/3316
 
Source The Indian Journal of Animal Sciences; Vol 78, No 1 (2008)
0367-8318
 
Language eng
 
Relation http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/3316/1348
 
Rights Copyright (c) 2014 The Indian Journal of Animal Sciences