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Protective action of dietary protein against monocrotophos toxicity on some biochemical constituents in rats

Indian Agricultural Research Journals

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Title Protective action of dietary protein against monocrotophos toxicity on some biochemical constituents in rats
 
Creator Sharma, Neeta Raj
Kushwah, Ameeta
Kushwah, H S
 
Subject Biochemical constituents; Dietary protein; Monocrotophos; Rats
 
Description The effect of a single or repeated oral dose of monocrotophos (2 mg/kg body weight) on certain biochemical constituents was studied in the blood and liver of rats maintained under normal, protein deficient and protein supplemented dietary conditions. Acute administration at varying intervals induced variable responses. A hyperglycemic and glycogenolytic impact at 12 hr was followed by enhanced glycogenesis accompanied by hypoglycemia at 24 hr in normal rats. In protein malnourished rats, a pronounced hyperglycemia associated with hypolactemia was noticed at 6 hr. Blood lactic acid level continued to be depressed indicating muscular weakness. Chronic exposure of pesticide elevated blood glucose and hepatic lactic acid levels in normal rats. In protein deprived animals, hyperglycemia and hyperlactemia with a concomitant fall in hepatic glycogen and lactic acid were observed. The animals were able to combat the toxic stress of monocrotophos on biochemical constituents when fed on a protein rich diet (20°0) A hyperlacternic Impact noticed on 7th or 15th day was also alleviated on 30th and 60th day post treatment.
 
Publisher Directorate of Knowledge Management in Agriculture
 
Contributor —
 
Date 2012-07-25
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
—
 
Format application/pdf
 
Identifier http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/22342
 
Source The Indian Journal of Animal Sciences; Vol 68, No 10 (1998)
0367-8318
 
Language eng
 
Relation http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/22342/10984
 
Rights Copyright (c) 2014 The Indian Journal of Animal Sciences