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Genetic variability of growth hormone gene and its association with growth traits in Sirohi breed of goat

Indian Agricultural Research Journals

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Title Genetic variability of growth hormone gene and its association with growth traits in Sirohi breed of goat
 
Creator KUMAR, S
DIXIT, S P
GUPTA, S C
VYAS, M K
KAUR, JAGDEEP
 
Subject Association; Goat; Growth hormone gene; Growth traits; Polymorphism; Sirohi breed;Single strand conformation
 
Description Genetic variations in the caprine growth hormone (c-GH. Gene) were investigated by single strand conformation polymorphism (SSCP) analysis of 8 amplified fragments covering almost the entire gene (approx 2.5 kb) in 188 Sirohi goats and was associated with body weights at birth, 3, 6 and 9 months of age. SSCP analysis revealed 4 to 8 unique banding patterns across 8 studied fragments of GH. The promoter and region having exon 3 showed higher level of polymorphism with 8 variants. The fragments consisting of exon 1, exon 4 and exon 5 revealed 6 variants. SSCP patterns in the promoter region had significantly influenced the birth weight. The SSCP variants in fragments consisting of exonic regions had also influenced the body weight at different ages in breed of goat. SSCP analysis has indicated the possibility of marker assisted selection for higher body weight at different ages in Sirohi breed of goat.
 
Publisher Directorate of Knowledge Management in Agriculture
 
Contributor —
 
Date 2011-03-11
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
—
 
Format application/pdf
 
Identifier http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/4807
 
Source The Indian Journal of Animal Sciences; Vol 81, No 3 (2011)
0367-8318
 
Language eng
 
Relation http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/4807/2037
 
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