Record Details

Bovine Angptl6 gene effects on growth traits in three Chinese native cattle breeds

Indian Agricultural Research Journals

View Archive Info
 
 
Field Value
 
Title Bovine Angptl6 gene effects on growth traits in three Chinese native cattle breeds
 
Creator LI, AIMIN
LAN, XIANYONG
MA, YUN
LIU, DONG
CAI, HANFANG
LE, CHUZHAO
CHEN, HONG
 
Subject Angptl6 gene; Cattle; Growth traits; Polymorphism
 
Description As a circulating orphan peptide secreted by liver, Angptl6 gene might have great effects on growth and development of animals. The objective of this study was to explore sequence variants (SVs) of Angptl6 and to analyze their associations with growth traits in 737 individuals belonging to 3 Chinese native cattle. Herein, 3 variants were revealed by DNA pools sequencing and PCR-RFLP (or ACRS-PCR-RFLP) methods. These SVs were located at nt 2359, nt 2403 and nt 3258 (viz. SV1, SV2, SV3) respectively. All the analyzed populations were at Hardy-Weinberg equilibrium by χ2-test. The linkage disequilibrium (LD) and haplotype analyses of 3 SVs revealed 8 different haplotypes. Thereinto, 2 dominant haplotypes (TCG and CCG) occurred with a frequency of 63.17% and 18.67% respectively. Association analysis showed the SV1 was significantly associated with BLI-6, and the SV2 and SV3 were significantly associated with CGI-24 and BHI-6 of individuals of Nanyang breed respectively. Further, combined SVs analysis revealed the ADG-18 of individuals with diplotype TC-CC-GG was higher than other combined genotypes in SV1-SV2-SV3 locus. Moreover, CG-18 with TC-GG and ADG-18 with TT-GT were preponderant in SV1-SV3 locus. Thus, 3 SVs showed great comprehensive effects on growth traits of Nanyang cattle, which indicated that they could be contributed to genetic and breeding programmes in cattle. Although there was no sufficient evidence these SVs greatly effect on the growth traits of cattle, the significant effects of these variants with these parameters could not be ignored
 
Publisher Directorate of Knowledge Management in Agriculture
 
Contributor —
 
Date 2012-11-19
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
—
 
Format application/pdf
 
Identifier http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/25154
 
Source The Indian Journal of Animal Sciences; Vol 82, No 11 (2012)
0367-8318
 
Language eng
 
Relation http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/25154/11705
 
Rights Copyright (c) 2014 The Indian Journal of Animal Sciences