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Production of high titered immunoreactive serum against FMDV

Indian Agricultural Research Journals

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Title Production of high titered immunoreactive serum against FMDV
 
Creator DECHAMMA, H J
KUMAR, C ASHOK
NAGARAJ, G
REDDY, G R
SURYANARAYANA, V V S
 
Subject Foot-and-mouth disease; Diagnosis; ELISA; Epitope; Pichia pastoris
 
Description Currently inactivated purified foot-and-mouth disease virus of various serotypes are used to raise type specific sera, which is laborious and involves the risk of handling live virus. Alternatively immunoreactive proteins produced in heterologous host system are an unlimited source of antigen for the production of diagnostic reagents. However, shorter peptides elicit low antibody titred sera. Hence the present study was taken up to evaluate the immune response ofa nlononler and compare with that ofa tetramer protein carrying inlmunoreactive epitopes ofFMDVserotype'0' .The research attempt of using specific recombinant antigen inmultilner form improve'd the immune response by increasing titre of the serum. 
 
Publisher Directorate of Knowledge Management in Agriculture
 
Contributor —
 
Date 2011-03-15
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
—
 
Format application/pdf
 
Identifier http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/4941
 
Source The Indian Journal of Animal Sciences; Vol 78, No 11 (2008)
0367-8318
 
Language eng
 
Relation http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/4941/2072
 
Rights Copyright (c) 2014 The Indian Journal of Animal Sciences