Record Details

Adaptation of R2B strain of Newcastle disease virus in vero cells

Indian Agricultural Research Journals

View Archive Info
 
 
Field Value
 
Title Adaptation of R2B strain of Newcastle disease virus in vero cells
 
Creator JOSHI, NAMITA
GARG, S K
CHANDRA, RAJESH
RAO, V D P
 
Subject Adaptation in vero cells, Newcastle disease, Newcastle disease virus
 
Description In quest of a cell culture adapted vaccine strain for Newcastle disease (ND), the R2B strain virus (NDV) was propagated in vero cells. The growth and adaptation of virus were assessed by haemagglutination (HA) and infectivity titres and by study of cytopathic effects (CPE). The virus adapted well to vero cells and produced characteristic cytopathic effects like formation of syncytia, stellate cells, cytoplasmic vacuolation and intracytoplasmic inclusion bodies. With the increase in passage level, the infectivity titre of virud increased 'gradually, but the HA titre decreased. The pathogenicity indices revealed reduction in the virulence of virus after adaptation to vero cells.
 
Publisher Directorate of Knowledge Management in Agriculture
 
Contributor —
 
Date 2014-02-04
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
—
 
Format application/pdf
 
Identifier http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/37467
 
Source The Indian Journal of Animal Sciences; Vol 72, No 3 (2002)
0367-8318
 
Language eng
 
Relation http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/37467/16788
 
Rights Copyright (c) 2014 The Indian Journal of Animal Sciences