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Expression analysis of myostatin and its receptor during the growth of adipose and muscle tissues in Meishan pig

Indian Agricultural Research Journals

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Title Expression analysis of myostatin and its receptor during the growth of adipose and muscle tissues in Meishan pig
 
Creator DENG, BING
DING, YI
WEN, JIANGHUI
PENG, JIAN
CHEN, CHEN
JIANG, SIWEN
 
Subject Adipose tissue; ACVR2B; Expression pattern; MSTN; Meishan pig
 
Description Myostatin (MSTN), mainly expressed in muscle, inhibits the growth of skeletal muscle and regulates the formation of adipose tissue. This study examined the expression of MSTN, activin-receptor-type II B (ACVR2B), peroxisome proliferator-activated receptor (PPAR) g and adipocyte specific fatty acid binding protein (aP2) in longissimus muscle, back fat and abdominal fat at the stages of 35-day, 2-month, 3-month, 4-month and 6–month Meishan pig respectively, using quantitative real-time PCR methods. Our results showed that the expressions of MSTN and its receptor (ACVR2B) were lower in adipose tissue (back fat and abdominal fat) than in muscle at all stages. Both MSTN and its receptor had different expression patterns in longissimus muscle, back fat and abdominal fat. MSTN had a weak correlation with aP2 and PPARg in longissimus muscle.The expression of MSTN had a positive correlation with aP2 and PPARg in back fat, however that of MSTN had a negative correlation with aP2 and PPARg in abdominal fat. Results indicated that those 3 tissues might respond differently at growing stages to MSTN signaling.
 
Publisher Directorate of Knowledge Management in Agriculture
 
Contributor —
 
Date 2012-01-02
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
—
 
Format application/pdf
 
Identifier http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/13835
 
Source The Indian Journal of Animal Sciences; Vol 82, No 1 (2012)
0367-8318
 
Language eng
 
Relation http://epubs.icar.org.in/ejournal/index.php/IJAnS/article/view/13835/6869
 
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