ICAR Research Data Repository for Knowledge Management
Molecular characterisation of a Theileria lestoquardi gene encoding a candidate sporozoite vaccine antigen
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View Archive Info| Field | Value | |
| Title |
Molecular characterisation of a Theileria lestoquardi gene encoding a candidate sporozoite vaccine antigen
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| Creator |
Skilton, Robert A.
Musoke, A.J. Nene, Vishvanath Wasawo, D.P.S. Wells, C.W. Spooner, P.R. Bishop, Richard P. Osaso, J. Nkonge, C. Latif, A. Morzaria, S.P. |
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| Subject |
theileria lestoquardi
vaccines sporozoa antigens antibodies |
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| Description |
Theileria are tick-transmitted, haemoprotozoan parasites infecting wild and domestic ungulates throughout many areas of the world. The most economically important species are T. parva and T. annulata which are pathogenic to cattle, and T. lestoquardi (syn hirci) which is pathogenic to sheep and goats. This report describes the cloning and analysis of the gene encoding the p67/SPAG-1 homologue of T. lestoquardi. This protein which is called SLAG-1 (sporozoite lestoquardi antigen 1), is predicted to have potential as a sporozoite - neutralisation antigen for inclusion in a sub-unit vaccine against T. lestoquardi infection of sheep and goats.
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| Date |
2000-04-15
2013-07-03T05:26:00Z 2013-07-03T05:26:00Z |
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| Type |
Journal Article
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| Identifier |
Molecular and Biochemical Parasitology;107(2): 309-314
0166-6851 https://hdl.handle.net/10568/33064 https://doi.org/10.1016/S0166-6851(99)00234-0 |
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| Language |
en
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| Rights |
Copyrighted; all rights reserved
Limited Access |
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| Format |
p. 309-314
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| Publisher |
Elsevier BV
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| Source |
Molecular and Biochemical Parasitology
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