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Molecular tools for characterisation of Theileria parva

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Title Molecular tools for characterisation of Theileria parva
 
Creator Morzaria, S.P.
Bishop, Richard P.
Nene, Vishvanath
Skilton, Robert A.
Geysen, D.
Mbogo, S.
 
Subject theileria parva
molecular biology
laboratory equipment
technology
immunological techniques
 
Description In order to discriminate different bovine Theileria species and to characterise genetic diversity in the pathogenic T. parva, a range of diagnostic and molecular tools have been developed. The diagnostic tools are based on recombinant antigens used in ELISAs and the molecular tools are based on parasite-specific repetitive sequences, random DNAs, antigen genes, mitochondrial DNA and small subunit ribosomal RNA genes. Using mainly southern blotting technique and PCR analysis, a comprehensive characterisation of the T. parva vaccine and field stocks has been obtained. These tools are increasingly being used in quality control of vaccines. Characterisation of parasite populations and epidemiology of theileriosis in conjunction with the deployment of live T. parva vaccines.
 
Date 1998
2014-10-31T06:21:46Z
2014-10-31T06:21:46Z
 
Type Conference Paper
 
Identifier https://hdl.handle.net/10568/50866
 
Language en
 
Rights Limited Access
 
Publisher Monduzzi Editore S.p.A.