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Therapeutic potential of endophytic bacteria from ethnomedicinal plants used by the traditional healers of North East India

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Title Therapeutic potential of endophytic bacteria from ethnomedicinal plants used by the traditional healers of North East India
 
Creator Tamreihao, K
Kshetri, Pintubala
Devi, Asem Kajal
Singh, Heikham Naresh
Rajiv, Chongtham
Singh, Thangjam Surchandra
Langamba, Pangambam
Langhu, Tabitha
Sharma, Susheel Kumar
Ansari, Meraj Alam
Datt, Shiv
Roy, Subhra Saikat
 
Subject Anticancer agents
Antimicrobial
Antioxidant
Endophytic bacteria
Ethnomedicinal plants
North East India
 
Description 618-628
North East Indian Himalayan Region (NEIHR) is endowed with a diverse ecosystem. The indigenous people of this region have good traditional knowledge to combat various diseases and physical ailments using ethnomedicinal plants that were gained through experience over years. Some of the plants have been incorporated in the conventional medicines. However, many of the plants have not been scientifically explored since they remain endemic to a particular region and the traditional healers kept it as secret knowledge. The majority of the endophyte of NEIHR belongs to genus Acinetobacter, Bacillus, Microbacterium, Pseudomonas, Serratia, and Streptomyces. Endophytic bacteria exhibit antimicrobial activities against important human pathogens such as Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica, Streptococcus pyogenes, Staphylococcus aureus, etc. Bioactive strains display potential anticancer and antioxidant activities. This review also incorporates some of the potential unexplored medicinal plants used by the ethnic population of this region for treating common diseases and the importance of exploring bioactive compounds from the associated bacteria. It will also highlight the prospects of discovering novel bioactive compounds that will have a new and novel mechanism of actions for combating the drug resistant pathogens.
 
Date 2023-09-29T11:24:47Z
2023-09-29T11:24:47Z
2023-07
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscpr.res.in/handle/123456789/62634
https://doi.org/10.56042/ijtk.v22i3.5750
 
Language en
 
Relation Int Cl.23: A61K 35/74, A61K 36/00
 
Publisher NIScPR-CSIR,India
 
Source IJTK Vol.22(3) [July 2023]