Predictive value of neoadjuvant chemotherapy on breast cancer subtypes evaluated by DCE-MRI and MRI perfusion parameters
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Title |
Predictive value of neoadjuvant chemotherapy on breast cancer subtypes evaluated by DCE-MRI and MRI perfusion parameters
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Creator |
Han, Bing
Pan, Shushu Ruan, Mei |
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Subject |
Biomarker Ki-67
Estrogen receptors HER-2 expression Progesterone receptors |
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Description |
807-812
Dynamic contrast enhanced MRI (DCE-MRI) is valuable for evaluating tumor angiogenesis. We aimed to predict the effects of neoadjuvant chemotherapy on breast cancer by DCE-MRI parameters. A total of 162 eligible patients were divided into response and non-response groups. Ktrans, Kep and Ve before, after two courses and at the end of neoadjuvant chemotherapy were compared. ER, PR, HER-2 and Ki-67 expressions in breast cancer tissues were detected by immunohistochemical staining. DCEMRI parameters at different ER, PR and HER-2 expression levels were compared, and their correlations with Ki-67 expression were analyzed. Ktrans and Kep of response group were lower after two courses and at the end of neoadjuvant chemotherapy than those before neoadjuvant chemotherapy (P |
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Date |
2023-10-10T05:50:37Z
2023-10-10T05:50:37Z 2023-09 |
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Type |
Article
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Identifier |
0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/62717 https://doi.org/10.56042/ijeb.v61i10.5841 |
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Language |
en
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Publisher |
NIScPR-CSIR, India
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Source |
IJEB Vol.61(10) [October 2023]
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