Record Details

Ameliorating effects of crude fucoidan extracts from Sargassum spp. obtained from Penghu Islands, Taiwan

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Ameliorating effects of crude fucoidan extracts from Sargassum spp. obtained from Penghu Islands, Taiwan
 
Creator Huang, Chun-Yung
wani, Henna Mohiud din
Hong, Yong-Han
Tsai, Yung-Hsiang
Li, Wei-Peng
Chiu, Yi-Chen
Chang, Jo-Shu
Dong, Cheng-Di
Patel, Anil Kumar
 
Subject Antidiabetic
Anti-inflammation
Antioxidant
Brown algae
Carbohydrate-digesting enzymes
Pancreatic cells
Reactive oxygen species (ROS)
Seaweed
 
Description 777-788
Sargassum spp., a predominant seaweed speciesin Taiwan's coastal waters, exhibits a broad spectrum of bioactivities. In
the present study, we investigated four Sargassum species viz., S. crassifolium, S. siliquosum, S. hemiphyllum,and
S. hemiphyllum var. chinense for various bioactivities. From the four species, we made eight fucoidan extracts, namely SC,
SCH, SS, SSH, SH, SHH, SHC, and SHCH with or without a compressional puffing pretreatment. The compressionalpuffing
process increased the extraction yield of fucoidan and decreased levels of impurities (proteins and polyphenols).
Among the eight fucoidans, SS (IC50 DPPH 0.46±0.01 mg/mL; IC50 ABTS•+ 0.09±0.00 mg/mL; FRAP value 67.4±0.9
μmol/g extract, vitamin C equivalent) and SHC (IC50 DPPH 0.53±0.17 mg/mL; IC50 ABTS•+ 0.11±0.00 mg/mL; FRAP
value 55.1±0.6 μmol/g extract, vitamin C equivalent) displayed the highest antioxidant activity; SS (36.4±10.1% at 5 mg/mL
for 𝛼-amylase; 96.3±0.2% at 1 mg/mL for 𝛼-glucosidase) and SHC (35.0±2.2% at 5 mg/mL for 𝛼-amylase; 96.5±0.2% at
1 mg/mL for 𝛼-glucosidase) showed the strongest 𝛼-amylase and 𝛼-glucosidase inhibitory activities; SH, SHH and SHC had
the most potent anti-inflammatory activity; and SHH had a greatest protective effect against damage to pancreatic cells.
Hence, SS, SH, SHH, and SHC may be effective health-promoting agents for nutraceutical products.
 
Date 2023-10-10T05:57:31Z
2023-10-10T05:57:31Z
2023-09
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/62721
https://doi.org/10.56042/ijeb.v61i10.1794
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJEB Vol.61(10) [October 2023]