ICAR Research Data Repository for Knowledge Management
Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies
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View Archive Info| Field | Value | |
| Title |
Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies
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| Creator |
McKeever, Declan J.
Taracha, E.L.N. Morrison, W. Ivan Musoke, A.J. Morzaria, S.P. |
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| Subject |
theileria parva
vaccines tickborne diseases immune response east coast fever immunological diseases parasitology |
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| Description |
Theileria parva is an intracellular sporozoan parasite that infects and transforms bovine lymphocytes, causing a severe lymphoproliferative disease known as East Coast fever in eastern, central and southern Africa. In this article, Declan McKeever and colleagues summarize the current understanding of immune mechanisms provoked by the parasite with regard to their role in both pathogenesis and protection. In particular, the influence of genomic polymorphism in parasite and host on the development of immunity is discussed, along with the evolution of current vaccine development strategies as a result of immunological research on the disease.
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| Date |
1999-07
2013-07-03T05:26:04Z 2013-07-03T05:26:04Z |
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| Type |
Journal Article
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| Identifier |
Parasitology Today;15(7): 263-267
0169-4758 https://hdl.handle.net/10568/33104 https://doi.org/10.1016/S0169-4758(99)01465-9 |
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| Language |
en
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| Rights |
Copyrighted; all rights reserved
Limited Access |
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| Format |
p. 263-267
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| Publisher |
Elsevier BV
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| Source |
Parasitology Today
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