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CRISPR for accelerating genetic gains in under-utilized crops of the drylands: Progress and prospects

OAR@ICRISAT

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Relation http://oar.icrisat.org/12241/
https://www.frontiersin.org/articles/10.3389/fgene.2022.999207/full
https://doi.org/10.3389/fgene.2022.999207
 
Title CRISPR for accelerating genetic gains in under-utilized crops of the drylands: Progress and prospects
 
Creator Sharma, K K
Palakolanu, S R
Bhattacharya, J
Shankhapal, A R
Bhatnagar-Mathur, P
 
Subject Genetic Engineering
Genetics and Genomics
Food Security
 
Description Technologies and innovations are critical for addressing the future food system needs where genetic resources are an essential component of the change process. Advanced breeding tools like “genome editing” are vital for modernizing crop breeding to provide game-changing solutions to some of
the “must needed” traits in agriculture. CRISPR/Cas-based tools have been rapidly repurposed for editing applications based on their improved efficiency, specificity and reduced off-target effects. Additionally, precise gene-editing
tools such as base editing, prime editing, and multiplexing provide precision in stacking of multiple traits in an elite variety, and facilitating specific and targeted crop improvement. This has helped in advancing research and delivery of products in a short time span, thereby enhancing the rate of genetic gains. A special focus has been on food security in the drylands through crops including millets, teff, fonio, quinoa, Bambara groundnut, pigeonpea and
cassava. While these crops contribute significantly to the agricultural economy and resilience of the dryland, improvement of several traits including increased stress tolerance, nutritional value, and yields are urgently
required. Although CRISPR has potential to deliver disruptive innovations, prioritization of traits should consider breeding product profiles and market segments for designing and accelerating delivery of locally adapted and
preferred crop varieties for the drylands. In this context, the scope of regulatory environment has been stated, implying the dire impacts of unreasonable scrutiny of genome-edited plants on the evolution and progress of much-needed technological advances.
 
Publisher Frontiers Media
 
Date 2022-10-06
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Rights cc_attribution
 
Identifier http://oar.icrisat.org/12241/1/Frontiers%20in%20Genetics_13_01-20_2022.pdf
Sharma, K K and Palakolanu, S R and Bhattacharya, J and Shankhapal, A R and Bhatnagar-Mathur, P (2022) CRISPR for accelerating genetic gains in under-utilized crops of the drylands: Progress and prospects. Frontiers in Genetics (TSI), 13. pp. 1-20. ISSN 1664-8021