Chemical composition and antibacterial activity of the essential oil and extract from Mentha longifolia against Helicobacter pylori
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Title |
Chemical composition and antibacterial activity of the essential oil and extract from Mentha longifolia against Helicobacter pylori
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Creator |
Kacho, Hanie Ahmadpour
Kazemi, Sohrab Farhadi, Pezhman |
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Subject |
Antimicrobial activity
Chemical composition Essential oil and extract Helicobacter pylori Mentha longifolia |
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Description |
458-463
Helicobacter pylori infection is prevalent, affecting almost half of the world's population. Eradicating H. pylori with antibiotics is a global challenge due to medication resistance. Developing new treatment regimens is one of the most important tactics for combating medication resistance. Herbal treatments have attracted a lot of interest recently among the many H. pylori infection adjunct therapies. M. longifolia is an edible plant found in northern Iran; its leaves have traditionally been used to cure gastrointestinal ailments. This study aims to determine the chemical composition of the essential oil (EO) derived from M. longifolia leaves using GC-MS and assess the anti-H. pylori activity of the EO and methanolic extract using the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) methods. Results showed that the main components of M. longifolia EO were cis-Piperitenone oxide (67.064%), piperitenone oxide (9.135%), L-Menthone (5.745%), Trans Caryophyllene (5.271%) and Eucalyptol (3.524%). M. longifolia EO exhibited the greatest anti-H. pylori activity (MIC=187 μg/mL), while the methanolic extract was (MIC=1500 μg/mL). The phytochemicals studied in this study have the potential to be utilized as adjuvant therapy with standard antibiotics against H. pylori. |
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Date |
2023-10-26T06:52:53Z
2023-10-26T06:52:53Z 2023-09 |
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Type |
Article
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Identifier |
0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscpr.res.in/handle/123456789/62802 https://doi.org/10.56042/ijnpr.v14i3.4044 |
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Language |
en
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Relation |
Int. cl. (2021.01)−A61K 36/00, A61K 36/53, A61P 31/00
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Publisher |
NIScPR-CSIR, India
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Source |
IJNPR Vol.14(3) [September 2023]
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