Record Details

Pangenomic analysis identifies structural variation associated with heat tolerance in pearl millet

OAR@ICRISAT

View Archive Info
 
 
Field Value
 
Relation http://oar.icrisat.org/12283/
https://www.nature.com/articles/s41588-023-01302-4
https://doi.org/10.1038/s41588-023-01302-4
 
Title Pangenomic analysis identifies structural variation associated with heat tolerance in pearl millet
 
Creator Yan, H
Sun, M
Zhang, Z
Jin, Y
Zhang, A
Lin, C
Wu, B
He, M
Xu, B
Wang, J
Qin, P
Mendieta, J P
Nie, G
Wang, J
Jones, C S
Feng, G
Srivastava, R K
Zhang, X
Bombarely, A
Luo, D
Jin, L
Peng, Y
Wang, X
Ji, Y
Tian, S
Huang, L
 
Subject Plant Genetics
Genetics and Genomics
 
Description Pearl millet is an important cereal crop worldwide and shows superior heat tolerance. Here, we developed a graph-based pan-genome by assembling ten chromosomal genomes with one existing assembly adapted to different climates worldwide and captured 424,085 genomic structural variations (SVs).
Comparative genomics and transcriptomics analyses revealed the expansion of the RWP-RK transcription factor family and the involvement of endoplasmic reticulum (ER)-related genes in heat tolerance. The overexpression of one RWP-RK gene led to enhanced plant heat tolerance and transactivated ER-related genes quickly, supporting the important roles of RWP-RK transcription factors and ER system in heat tolerance. Furthermore, we found that some SVs affected the gene expression associated with heat tolerance and SVs surrounding ER-related genes shaped adaptation to heat tolerance during domestication in the population. Our study provides a comprehensive genomic resource revealing insights into heat tolerance and laying a foundation for generating more robust crops under the changing climate.
 
Publisher Nature Publishing Group
 
Date 2023-03-02
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Rights cc_attribution
 
Identifier http://oar.icrisat.org/12283/1/Nature%20Genetics_55_507-518_2023.pdf
Yan, H and Sun, M and Zhang, Z and Jin, Y and Zhang, A and Lin, C and Wu, B and He, M and Xu, B and Wang, J and Qin, P and Mendieta, J P and Nie, G and Wang, J and Jones, C S and Feng, G and Srivastava, R K and Zhang, X and Bombarely, A and Luo, D and Jin, L and Peng, Y and Wang, X and Ji, Y and Tian, S and Huang, L (2023) Pangenomic analysis identifies structural variation associated with heat tolerance in pearl millet. Nature Genetics, 55. pp. 507-518. ISSN 1546-1718