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Multiplexed Host-Induced Gene Silencing of Aspergillus flavus Genes Confers Aflatoxin Resistance in Groundnut

OAR@ICRISAT

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Field Value
 
Relation http://oar.icrisat.org/12293/
https://www.mdpi.com/2072-6651/15/5/319
https://doi.org/10.3390/toxins15050319
 
Title Multiplexed Host-Induced Gene Silencing of Aspergillus flavus Genes Confers Aflatoxin Resistance in Groundnut
 
Creator Prasad, K
Yogendra, K
Sanivarapu, H
Rajasekaran, K
Cary, J W
Sharma, K K
Bhatnagar-Mathur, P
 
Subject Groundnut
Aflatoxins
 
Description Aflatoxins are immunosuppressive and carcinogenic secondary metabolites, produced by the filamentous ascomycete Aspergillus flavus, that are hazardous to animal and human health. In this study, we show that multiplexed host-induced gene silencing (HIGS) of Aspergillus flavus genes essential for fungal sporulation and aflatoxin production (nsdC, veA, aflR, and aflM) confers enhanced resistance to Aspergillus infection and aflatoxin contamination in groundnut (
 
Publisher MDPI
 
Date 2023-05-05
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Rights cc_attribution
 
Identifier http://oar.icrisat.org/12293/1/Toxins_15_5_1-23_2023.pdf
Prasad, K and Yogendra, K and Sanivarapu, H and Rajasekaran, K and Cary, J W and Sharma, K K and Bhatnagar-Mathur, P (2023) Multiplexed Host-Induced Gene Silencing of Aspergillus flavus Genes Confers Aflatoxin Resistance in Groundnut. Toxins (TSI), 15 (5). pp. 1-23. ISSN 2072-6651