Multiplexed Host-Induced Gene Silencing of Aspergillus flavus Genes Confers Aflatoxin Resistance in Groundnut
OAR@ICRISAT
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Relation |
http://oar.icrisat.org/12293/
https://www.mdpi.com/2072-6651/15/5/319 https://doi.org/10.3390/toxins15050319 |
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Title |
Multiplexed Host-Induced Gene Silencing of Aspergillus flavus Genes Confers Aflatoxin Resistance in Groundnut
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Creator |
Prasad, K
Yogendra, K Sanivarapu, H Rajasekaran, K Cary, J W Sharma, K K Bhatnagar-Mathur, P |
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Subject |
Groundnut
Aflatoxins |
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Description |
Aflatoxins are immunosuppressive and carcinogenic secondary metabolites, produced by the filamentous ascomycete Aspergillus flavus, that are hazardous to animal and human health. In this study, we show that multiplexed host-induced gene silencing (HIGS) of Aspergillus flavus genes essential for fungal sporulation and aflatoxin production (nsdC, veA, aflR, and aflM) confers enhanced resistance to Aspergillus infection and aflatoxin contamination in groundnut (
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Publisher |
MDPI
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Date |
2023-05-05
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Language |
en
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Rights |
cc_attribution
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Identifier |
http://oar.icrisat.org/12293/1/Toxins_15_5_1-23_2023.pdf
Prasad, K and Yogendra, K and Sanivarapu, H and Rajasekaran, K and Cary, J W and Sharma, K K and Bhatnagar-Mathur, P (2023) Multiplexed Host-Induced Gene Silencing of Aspergillus flavus Genes Confers Aflatoxin Resistance in Groundnut. Toxins (TSI), 15 (5). pp. 1-23. ISSN 2072-6651 |
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