Exploration of urease-mediated biomineralization for defluoridation by Proteus columbae MLN9 with an emphasis on its genomic characterization
OAR@ICRISAT
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Relation |
http://oar.icrisat.org/12300/
https://www.sciencedirect.com/science/article/abs/pii/S2213343723005304 https://doi.org/10.1016/j.jece.2023.109791 |
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Title |
Exploration of urease-mediated biomineralization for defluoridation by Proteus columbae MLN9 with an emphasis on its genomic characterization
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Creator |
Let, M
Majhi, K Halder, U De, A Saha, D Chitikineni, A Roychowdhury, T Varshney, R K Bandopadhyay, R |
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Subject |
Agriculture
Genetics and Genomics |
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Description |
Fluoride (F-) contamination of groundwater is a silent killer of human health that has now become a global problem. In the present study, we sought to isolate fluoride-resistant, urease producing bacteria from F- contaminated groundwater to evaluate their potential F- biomineralization. Strain MLN9, isolated from the fluoride-contaminated village of Madhabpur in Birbhum, could resist up to 5600 mg L−1 F- concentration. Taxonomic classification of strain MLN9 based on whole genome sequence identified it as Proteus columbae MLN9. Strain MLN9 showed 88.9% of maximum F- removal efficiency at pH 8.0, 1.0 g L−1 CaCl2, and 10.0 g L−1 urea concentration. Scanning electron micrographs showed dense and porous biological crystal precipitates surrounding the surface of the bacterial cells, and the adherence of F- to the cell surface was confirmed by the energy dispersion spectrum. Moreover, the X-ray diffraction pattern showed that the F- precipitates on the cell surface were biological crystals of Ca5(PO4)3F and CaF2. Genomic analysis of strain MLN9 revealed the presence of crcB gene homologs possibly encoding F- transporters and urease regulatory proteins such as UreA, UreB, UreC, UreD, and UreG suggesting a role in defluoridation. Our findings provide new insights into the urease based MICP technology using a noble bacterium Proteus columbae MLN9 for fluoride removal.
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Publisher |
Elsevier
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Date |
2023-03-27
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Type |
Article
PeerReviewed |
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Identifier |
Let, M and Majhi, K and Halder, U and De, A and Saha, D and Chitikineni, A and Roychowdhury, T and Varshney, R K and Bandopadhyay, R (2023) Exploration of urease-mediated biomineralization for defluoridation by Proteus columbae MLN9 with an emphasis on its genomic characterization. Journal of Environmental Chemical Engineering, 11 (3). ISSN 2213-3437
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