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Correlation between cervical thickness and histological severity of cervical intraepithelial neoplasia: A transvaginal ultrasound investigation

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Title Correlation between cervical thickness and histological severity of cervical intraepithelial neoplasia: A transvaginal ultrasound investigation
 
Creator He, Yeping
Guo, Jianfeng
 
Subject Adenocarcinoma
Adenosquamous carcinoma
Cervical cancer
 
Description 953-958
Cervical cancer, with estimated incidences of >0.6 million worldwide, is considered as one among the top 10 cancers. As an affordable technique, ultrasonography is commonly used in gynecologic patient management. However, detection of cervical cancer at early stage, particularly cervical intraepithelial neoplasia (CIN) is difficult to be diagnosed directly on ultrasound. In this context, here, we looked on the possible correlation between the thickness of the cervix and the grade of cervical intraepithelial neoplasia (CIN) for diagnosis purpose. We measured the cervical thickness in 120 women with abnormal cervical cancer screening tests by transvaginal ultrasound examination (TVUS) in the
mid-sagittal plane. All of the women had at least one biopsy.
The cervical thickness calculated in each CIN grade and the receiver operating characteristic (ROC) curves were used to determine the best cut-off value of the cervical thickness to predicted CIN2 or higher (CIN2+, including CIN2 and CIN3).The ROC curve is produced by calculating and plotting the true positive rate against the false positive rate for a single classifier at a variety of thresholds. For example, in logistic regression, the threshold would be the predicted probability of an observation belonging to the positive class. Cervical thickness increased with histological severity,with a Spearmancorrelation coefficient of 0.549 (P
 
Date 2023-11-28T06:58:12Z
2023-11-28T06:58:12Z
2023-12
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/62963
https://doi.org/10.56042/ijeb.v61i12.6813
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJEB Vol.61(12) [December 2023]