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DEMONSTRATION OF ANTIVIRAL ACTIVITY OF IVERMECTIN AGAINST R2B STRAIN OF NEWCASTLE DISEASE VIRUSINFECTED 9- DAY OLD CHICKEN EGGS 2

Indian Agricultural Research Journals

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Title DEMONSTRATION OF ANTIVIRAL ACTIVITY OF IVERMECTIN AGAINST R2B STRAIN OF NEWCASTLE DISEASE VIRUSINFECTED 9- DAY OLD CHICKEN EGGS 2
 
Creator T. Jagadeesh
G. Sathish
M. Parthiban
P. Raja
G. Sarathchandra
 
Subject Ivermectin
R 2 B strain
Haemagglutination test
 
Description Antiviral activity of ivermectin was examined against R2B strain of Newcastle disease virus in 9 - day old embryonated chicken eggs. Five distinct concentrations (500, 250, 100, 50, 10 µg/mL) of ivermectin were used in the study. Haemagglutination test was performed to determine the antiviral activity of ivermectin by using chicken RBC. The results revealed that ivermectin can exert a significant antiviral activity against Newcastle disease virus at higher concentrations (500, 250 and 100 µg/ml) but with cytotoxic effects. On the contrary a moderate to weak antiviral activity without cytotoxicity was demonstrated at lower concentrations (50, 10 µg/ml).
 
Publisher Tamil Nadu Veterinary and Animal Sciences University
 
Date 2023-12-08
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://epubs.icar.org.in/index.php/IJVASR/article/view/145249
 
Source Indian Journal of Veterinary and Animal Sciences Research; Vol. 52 No. 4 (2023): IJVASR July - August 2023; 91-97
2347-2774
 
Language eng
 
Relation https://epubs.icar.org.in/index.php/IJVASR/article/view/145249/52994
 
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