ICAR Research Data Repository for Knowledge Management
Evaluation of Isooxazoline derivatives in the Treatment of Canine Demodicosis
Indian Agricultural Research Journals
View Archive Info| Field | Value | |
| Title |
Evaluation of Isooxazoline derivatives in the Treatment of Canine Demodicosis
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| Creator |
Pardeep Sharma
Abhishek Bansal |
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| Subject |
afoxolaner, Demodex canis, fluralaner, sarolaner
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| Description |
Canine demodicosis is a common dermatological condition observed indogs. The aim of this study was to evaluate the effectiveness of isooxazoline derivatives for the treatment of demodicosis compared to ivermectin.Forty-one dogs with demodicosis were treated with ivermectin (n=13), fluralaner(n=5), sarolaner(n=11) and afoxolaner (n=12),respectively. The mite count was evaluated on day 0, 28, 56 and 84 of treatment period. A single oral dose of isooxazoline derivatives reduced Demodex mite counts in skin scrapings by an average of 98.6% in all dogs by 28th day and 100% by 84th day. Single administration of ivermectin resulted to be only 76.8% effective. No adverse effects of drugs were observed in any of the dogs.
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| Publisher |
Indian Veterinary Association
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| Date |
2023-12-15
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| Type |
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion |
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| Format |
application/pdf
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| Identifier |
https://epubs.icar.org.in/index.php/IVJ/article/view/146481
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| Source |
The Indian Veterinary Journal; Vol. 100 No. 12 (2023): December, 2023; 25 - 28
0974-9365 0019-6479 |
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| Language |
eng
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| Relation |
https://epubs.icar.org.in/index.php/IVJ/article/view/146481/53414
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| Rights |
Copyright (c) 2023 The Indian Veterinary Journal
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