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Genetic characterization of infectious bursal disease virus isolates in Ethiopia

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Title Genetic characterization of infectious bursal disease virus isolates in Ethiopia
 
Creator Jenberie, S.
Lynch, Stacey E.
Kebede, F.
Christley, Robert M.
Gelaye, E.
Negussie, H.
Asmare, K.
Ayelet, G.
 
Subject animal diseases
genetics
 
Description The objective of the investigation was to characterize infectious bursal disease viruses (IBDV) circulating in commercial and breeding poultry farms in Ethiopia between 2009 and 2011. The nucleotide and deduced amino acid sequence for VP2 hypervariable region of ten IBDVs were determined by RT-PCR, sequenced and compared to well characterised IBDV isolates worldwide. IBDV genetic material was amplified directly from bursa or cell passaged material. Phylogenetically, Ethiopian IBDVs represented two genetic lineages: very virulent (vv) IBDVs or variants of the classical attenuated vaccine strain (D78). The nucleotide identity between Ethiopian vvIBDVs ranged between 0% to 2.6%. Ethiopian vvIBDVs are clustered phylogenetically with the African IBDV genetic lineage, independent of the Asian/European lineage. This report demonstrates the circulation of vvIBDV in commercial and breeding poultry farms in Ethiopia.
 
Date 2014-02
2013-11-03T13:35:22Z
2013-11-03T13:35:22Z
 
Type Journal Article
 
Identifier Jenberie, S., Lynch, S.E., Kebede, F., Christley, R., Gelaye, E., Negussie, H., Asmare, K. and Ayelet, G. 2013. Genetic characterization of infectious bursal disease virus isolates in Ethiopia. Acta Tropica 130: 39-43.
0001-706X
https://hdl.handle.net/10568/33888
https://doi.org/10.1016/j.actatropica.2013.09.025
 
Language en
 
Rights CC-BY-3.0
Open Access
 
Format p. 39-43
 
Publisher Elsevier BV
 
Source Acta Tropica