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Evaluation of xylazine-diazepam-ketamine anaesthesia in mules: Anaesthetic, haemato-biochemical, and blood gas studies

Indian Agricultural Research Journals

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Title Evaluation of xylazine-diazepam-ketamine anaesthesia in mules: Anaesthetic, haemato-biochemical, and blood gas studies
 
Creator DAR, K H
GUPTA, A K
BHADWAL, M S
GUPTA, S K
GUPTA, P
KUSHWAHA, R B
RAINA, R
 
Subject Blood gases
Diazepam
Ketamine
Mules
TIVA
Xylazine
 
Description The present study was conducted on 6 clinically healthy adult mules of both sexes (4 females and 2 castrated males), with the approval of IAEC, to evaluate the total intravenous anaesthesia with diazepam-ketamine mixture following xylazine premedication. The anaesthetic combination resulted in quick induction (1.84±0.52 min), prolonged sedation, good to moderate analgesia, moderate muscle relaxation, and smooth and quick recovery. The duration of anaesthesia was 15.21±0.64 min. During recovery, limb and head movements, sternal recumbency, standing ataxia, and normal gait were attained at 16.0±3.21min, 23.30±1.23min, 25.5±3.20 min, and 32.75±3.25 min, respectively, from the time of diazepam-ketamine administration. The anaesthetic combination did not have significant effect on rectal temperature, haemato-biochemical parameters, blood gases, electrolytes, and oxygen status except a significant progressive decrease in the heart rate form the base value up to 15 min after induction, returning to the base level by 45 min, and significant fluctuations in the respiratory rate within the physiological limits. The partial pressure of oxygen in arterial blooddecreased to below normal during anaesthesia, however, the oxygen saturation of haemoglobin and oxygen content of blood were well maintained throughout the period of anaesthesia. The combination can be used safely for moderate depth of anaesthesia in mules.
 
Publisher Indian Council of Agricultural Research
 
Date 2014-02-12
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier https://epubs.icar.org.in/index.php/IJAnS/article/view/37817
10.56093/ijans.v84i2.37817
 
Source The Indian Journal of Animal Sciences; Vol. 84 No. 2 (2014); 130–135
2394-3327
0367-8318
 
Language eng
 
Relation https://epubs.icar.org.in/index.php/IJAnS/article/view/37817/16958
 
Rights Copyright (c) 2014 The Indian Journal of Animal Sciences
https://creativecommons.org/licenses/by-nc-sa/4.0