Dose dependent effect of pregnant mare serum gonadotropin and human chorionic gonadotropin on in vitro maturation of goat oocytes
Indian Agricultural Research Journals
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Title |
Dose dependent effect of pregnant mare serum gonadotropin and human chorionic gonadotropin on in vitro maturation of goat oocytes
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Creator |
KOUAMO, J
KHARCHE, S D |
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Subject |
Goats
hCG In vitro maturation Oocytes PMSG |
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Description |
This study was aimed to evaluate the dose dependent effect of pregnant mare serum gonadotropin and human chorionic gonadotropin on in vitro maturation goat oocytes. The study was planned in 2 experiments. In the first experiment effect of pregnant mare serum gonadotropin supplementation on nuclear maturation of goat oocytes using 5 different concentrations of PMSG, was studied. The treatment was divided into group 1 (control medium containing TCM-199, sodium pyruvate (0.25mM), gentamycin (50µg/ml), L-glutamine (100µg/ml), estradiol 17-ß (1µg/ml), BSA (3mg/ml), supplemented with 10% FBS); group 2 (control medium + 10 IU/ml PMSG); group 3 (control medium + 20 IU/ml PMSG); group 4 (control medium + 30 IU/ml PMSG); group 5 (control medium + 40 IU/ml PMSG); and group 6 (control medium + 50 IU/ml PMSG). The oocytes of these treatment groups were matured in maturation media for 27 h in humidified atmosphere of 5% CO2 at 38.5°C in a CO2 incubator. The maturation rates achieved in groups 1–6 were 20.0, 48.51, 74.63, 74.15, 75.0 and 76.33%, respectively. In experiment 2, the effect of hCG supplementation on nuclear maturation of goat oocytes using 3 different concentrations of PMSG, was studied. Second experiment was divided into group 1 (control medium + 20 IU/ml PMSG +10IU/ml hCG), group 2 (control medium + 20 IU/ml PMSG +20IU/ml hCG) and group 3 (control medium + 20 IU/ml PMSG +30IU/ml hCG). The maturation rates achieved in groups 1–3 were 77.0, 85.19 and 84.22%, respectively. It can be concluded that supplementation of 20 IU/mL PMSG and 20IU hCG in maturation media significantly increased the maturation rate.
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Publisher |
Indian Council of Agricultural Research
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Date |
2014-04-16
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Type |
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion |
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Format |
application/pdf
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Identifier |
https://epubs.icar.org.in/index.php/IJAnS/article/view/39842
10.56093/ijans.v84i4.39842 |
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Source |
The Indian Journal of Animal Sciences; Vol. 84 No. 4 (2014); 410–414
2394-3327 0367-8318 |
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Language |
eng
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Relation |
https://epubs.icar.org.in/index.php/IJAnS/article/view/39842/17930
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Rights |
Copyright (c) 2014 The Indian Journal of Animal Sciences
https://creativecommons.org/licenses/by-nc-sa/4.0 |
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