Record Details

Multi-Sensory Integration Impairment in Patients with Minimal Hepatic Encephalopathy

Harvard Dataverse (Africa Rice Center, Bioversity International, CCAFS, CIAT, IFPRI, IRRI and WorldFish)

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Title Multi-Sensory Integration Impairment in Patients with Minimal Hepatic Encephalopathy
 
Identifier https://doi.org/10.7910/DVN/53W4LE
 
Creator Seo, Kyoungwon
Jun, Dae Won
Kim, Jae-kwan
Ryu, Hokyoung
 
Publisher Harvard Dataverse
 
Description Paper-and-pencil-based psychometric tests are the gold standard for diagnosis of cognitive dysfunction in liver disease. However, they take time, can be affected by demographic factors, and lack ecological validity. This study explored multi-sensory integration ability to discriminate cognitive dysfunction in cirrhosis. Thirty-two healthy controls and 30 cirrhotic patients were recruited. The sensory integration test presents stimuli from two different modalities (e.g., image/sound) with a short time lag, and subjects judge which stimuli appeared first. Repetitive tests reveal the sensory integration capability. Performance in the sensory integration test, psychometric tests, and functional near-infrared spectroscopy for patients was compared to controls. Sensory integration capability, the perceptual threshold to discriminate the time gap between an image and sound stimulus, was significantly impaired in cirrhotic patients with minimal hepatic encephalopathy (MHE) compared to controls (p
 
Subject Medicine, Health and Life Sciences
Sensory integration
 
Contributor Seo, Kyoungwon