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ABO Blood Type and Risk of Peyronie’s Disease in Japanese Males

Harvard Dataverse (Africa Rice Center, Bioversity International, CCAFS, CIAT, IFPRI, IRRI and WorldFish)

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Title ABO Blood Type and Risk of Peyronie’s Disease in Japanese Males
 
Identifier https://doi.org/10.7910/DVN/EWHLPH
 
Creator Yozo Mitsui
 
Publisher Harvard Dataverse
 
Description Purpose: Although multiple mechanisms associated with Peyronie’s disease (PD) have been proposed, details regarding etiologic factors, especially genetic, remain unclear. We examined the relationship of the ABO blood type system, known as a
genetic factor associated with susceptibility to a number of diseases, with PD in Japanese males.
Materials and Methods: We compared 202 Japanese PD patients treated with surgery at our hospital between March 2004 and December 2019 with 846 randomly selected non-PD male patients who underwent urological surgery during the same
period regarding distribution of ABO blood types. In addition, we assessed the risk of PD according to blood type group among all study participants using odds ratio (OR) and 95% confidence interval (CI) calculations.
Results: The distribution of individual blood types in the control group was nearly the same as that in the general Japanese population. In contrast, O, A, B, and AB blood types were noted in 37.6%, 36.1%, 14.9% and 11.4%, respectively, of the PD
patients, which was significantly different from the control group, where blood type O was found in 29.1% and B in 23.2% (p
 
Subject Medicine, Health and Life Sciences
 
Contributor Park, Hyun Jun